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That movie is one of my unsung favourites.

The WB cartoons have also been often cited as one of the sources of humour copied by writers and comedians to this day- along with The Muppet Show. I still love them.

They shoulda turned left at Albuquerque.

Yes, Bergen was,

I meant 2 out of three. Chris Jones is good as entertainment for other CFL fans, but a pestilence for Elk fans.

Don't know if has been posted already, but Augustine has re-signed with the Blue.

I can see why they have kept Legghio around- a ton of potential and young enough to be around for a decade or more if he gets his poop together.

Well, one out of three ain't too bad.

O'Toole had zero chance to rein in the nutbars in the party. They resented that he did not throw himself into the extreme anti-science, gun-promoting agenda "Christian" agenda right off the hop, and the knives were sharpened. The only reason the CPC got close to a majority in the early part of the election was that O'Toole was perceived by voters as pragmatic and progressive, and that doomed him within the party.

I cannot recall the state, but apparently an atheistic group has filed a lawsuit demanding that the Bible be removed from all schools for its promotion of incest, human sacrifice, killing of dissidents who wear the wrong clothes or plant the wrong crops, slavery and genocide.

Trump won only by voicing lies, triggering racial fears and hatred, and by a campaign of voter suppression and gerrymandering. He got away with it once and the GOP has realized that they have to corrupt the political system even further to stand another chance.

You are seeing what you choose to see. The housing shortage is being market-driven, inflation reflects the slowing of income and expenditures the federal government had to make due to the COVID crisis. Unemployment is low, so where is your argument? The majority of Canadians support progressive policies, including carbon pricing, and rather than accept restrictions on firearms and carbon pricing, the CPC rank and file chose to kill O'Toole the messenger. He was intelligent enough to realize that these policies resonated with the majority of Canadians, and he paid the price for saying it out loud. Instead of realizing that they are out of step with history and Canadian public opinion, they have retreated into unpopular dogma and are wringing their hands in self-pity.

I suspect that many relatively sane CPC MPs and their followers are willing to countenance a far-right leader (and all the luddite policies) so long as it means that the Liberals lose. This, essentially means sacrificing principles for a shot at power. The GOP headed in that direction some 30 years ago, and look where that took them.

Sheer is a "leader"????

(Another one bites the dust) Anti-Vax Priest Who Claimed Vaccines Contain ‘Aborted Embryos’ Dies of COVID An Italian priest who shunned COVID-19 vaccines over the false belief that they contain “aborted embryos” has died at the age of 51 after battling coronavirus for several weeks. Don Paolo Romeo had resisted pleas to get vaccinated from friends and colleagues who tried to talk sense into him, according to the L’Unione Sarda newspaper. Romeo, who served as parish priest at Santo Stefano Abbey in Genoa, had clung to the conspiracy theory espoused by followers of French Catholic Archbishop Marcel François Marie Joseph Lefebvre: that vaccines are made using cells from aborted embryos. (This claim is false and has been debunked even by the United States Conference of Catholic Bishops, which noted in a statement released in January that “neither Pfizer nor Moderna used an abortion-derived cell line in the development or production of the vaccine.”) Fetal cell lines, which are cloned copies of cells taken from elective abortions that were performed decades ago, were used in the testing of vaccines and have frequently been used for the testing of widely used drugs like ibuprofen and aspirin. But even the Vatican has stressed that COVID-19 vaccines are “morally acceptable” and “can be used in good conscience” during the pandemic. Romeo refused to be swayed, however, and he continued to celebrate Mass despite coronavirus infections spreading. He was diagnosed with the virus in January and was admitted to a hospital near his church after his health rapidly deteriorated, according to local reports. Anti-Vax Priest Don Paolo Romeo, Who Claimed Vaccines Contain ‘Aborted Embryos,’ Dies of COVID (thedailybeast.com)

It is starting to look like a circus, and going to get weirder and weirder.

So far it looks like the defence will be set soon and even better than last year, given the continuity. The only possible fly in the ointment might be Richie Hall's health.

Fact-checker torches Chip Roy for circulating false conspiracy about Canadian PM fleeing to the United States Fact-checkers are pushing back against Rep. Chip Roy's (R-Texas) false claims about Canadian Prime Minister Justin Trudeau. According to The Daily Beast, Roy's post stems from a conspiracy about Trudeau fleeing Canada "in fear of a group of truck drivers who are protesting vaccine mandates" in Ottawa, Canada. In a series of Twitter posts shared on January 31, Roy slammed Trudeau and even called for him to be deported from the states even though he is not in the country. With a photo of Trudeau, Roy tweeted, “Is there a more gutless and cowardly display than a tyrant on the run?” The following day, he tweeted: "If Justin Trudeau is hiding in the United States, we should return him to Canada and make him face his own people immediately." He added, "No safe haven for fleeing COVID tyrants. #LiveFree #DeportTrudeau." And he included a graphic that featured a promotional logo for his congressional campaign, a photo of Trudeau, and the words "DEPORT TRUDEAU." Fact-checker torches Chip Roy for circulating false conspiracy about Canadian PM fleeing to the United States - Alternet.org

I have little doubt he was playing for minimum wage for the honour (?) of playing for the Riders. He can retire knowing that he did his bit to create the season the Riders had.

Isn't Argula some sort of veggie?

O'Toole was doomed from the start. He somehow convinced himself that he could reconcile oil and water and unsurprisingly failed. PCs have a long and sordid history of assassinating leaders who do not produce immediate results and this is no exception. No matter who is chosen next, he/she will meet the same fate and the party will inevitably split. The intoxicating success of Harper simply delayed the inevitable.

This Breakthrough Cancer Treatment Has Prevented Leukemia Relapse for Over a Decade Doug Olson was 49 years old with a wife and four kids when he was diagnosed with chronic lymphocytic leukemia in 1996. His initial treatments were pretty successful, but by 2010 almost 50 percent of his bone marrow was cancerous again. That’s when he enrolled into a clinical trial of a new cancer therapy led by his oncologist, David Porter from the University of Pennsylvania’s Perelman Center for Advanced Medicine, together with one other patient. The experimental treatment, also known as CAR T-cell therapy, would tweak Olson's own immune cells to spot and kill leukemia cells, and reintroduce them into his body through blood infusion—something that previously showed promise only in trials on mice. Olson started physically feeling the results after just a couple of weeks. “That’s when Dr. Porter came into my hospital room and he announced, hot off the press, that 18 percent of my white cells were CAR T-cells,” Olson said during a press conference Tuesday. “I will tell you that moment, I was absolutely convinced that this thing was working and that I was gonna be okay.” The next week, Porter told Olson the clinicians couldn’t find a single cancer cell in his body. It’s been more than 10 years now, and Olson is still cancer free. In a peer-reviewed study published today, in the journal Nature, Porter and the clinicians who followed Olson’s journey document the experimental treatment and its results. The findings show that even after ten years, Olson and the other patient have remained cancer-free thanks to CAR T-cell therapy—validating its incredible efficacy and opening the door for its use in many more cases of leukemia and other cancers in the future. “It was an exciting new therapy, but we've all been involved in many, many, many, many different new therapies and it is rare to hit on something to work so dramatically,” said Porter, lead author of the new paper. “The responses have been beyond our, certainly my, wildest expectations.” T-cells are an essential component of the immune system. They can both direct other immune cells to attack invading pathogens, as well as kill pathogens themselves. T-cells live for a very long time, and can form a lifelong memory of what they’ve recognized before, like from viral exposure in childhood. In CAR T-cell therapy for cancer, a patient’s own T-cells are collected and genetically engineered to produce a molecule called a Chimeric Antigen Receptor, or CAR. These CARs enable the T-cells to identify cancer cells with a laser-eyed focus and eliminate them. Millions upon millions of CAR T-cells are made in the lab, and then re-inserted in the patient through a blood infusion. In theory, CAR T-cells should be able to swoop in and clear out tumor cells with extreme precision and speed. And since they retain such good memory and can circulate in the body for a long time, they should be able to prevent the same cancer from popping up again. But Porter and his colleagues were stunned to see the therapy prevent a resurgence of cancer cells for such a long time in this latest study, given the high rate of remission for leukemia. They suspect CAR T-cells evolve within patients over time to learn better ways to hunt down tumor cells. “[CAR T-cells are] wearing multiple hats,” Joseph Melenhorst, a UPenn immunologist and co-author of the new paper, told reporters Tuesday. “We've called these cells, you know, a living therapy. The major finding that shows in this paper is that 10 years down the road, you can find them, but they have evolved.” The researchers don’t know if there are still leukemia cells forming in Olson’s body and simply being rapidly killed by the CAR T-cells on patrol; or whether there has truly been an absence of cancerous activity in the patient since 2010. What they do know, however, is that when Olson’s CAR T-cells were taken out of his body and confronted with leukemia in the lab, they were still able to kill. Since that clinical trial in 2010, CAR T-cell therapy has now been FDA approved for six different indications, and acute leukemia is treated routinely with this therapy worldwide. But these are the first results to establish how long-lasting it could work for the tens of thousands who’ve already been treated. The major barrier for patients, unfortunately, is price. CAR T-cell therapy can cost anywhere from $300,000 to $500,000. Researchers are trying to create less expensive over-the-counter therapies that have the same approach, with cells made from other donors in large amounts. Then, hopefully, it’ll be possible to expand this therapy to tackle solid cancers too, like breast cancer, lung cancer, or pancreatic cancer. Trials are currently underway, but the results so far haven’t been particularly encouraging. And although the two cases explored in the new paper have had very positive outcomes, the long-term effects of CAR T-cell therapy still need more extensive study. Some patients report worse side-effects because CAR T-cells do have some unique toxicities. Even Olson’s positive outcome was tempered by a bout with tumor lysis syndrome, where the rapid destruction of cancer cells leads to an adverse immune reaction and causes flu-like symptoms like nausea, vomiting, and joint pains. And there are some instances where the CAR T-cells lose some of their efficacy, especially in trials against solid tumors. “The biology of long-lived persisting CAR T-cells isn’t fully understood,” Sara Ghorashian, a CAR T-cell researcher from University College London who was not involved in the study, told The Daily Beast. It’s not entirely clear yet why some patients will see CAR T-cells that last for years, while others might experience fading efficacy in less than six months. A host of unknown factors could be at play, and Ghorashian cautioned against extrapolating the findings to all CAR T therapy settings. Still, within the span of a decade, CAR T-cells have broken out as a game-changing form of cancer treatment. And findings like Porter’s and his colleague’s will only fuel more efforts to learn more about how this therapy works and how we can make it accessible to more patients who are fighting for their lives. CAR T-Cell Therapy Prevented Leukemia Cancer Remission in Patients for Over 10 Years (thedailybeast.com)

( Looks like a lot of Americans Frequent This Mexican Airport)